D position on computational modeling of integrin signaling

[aureliecarlier]

The department of Cell Biology-Inspired Tissue Engineering (cBITE) at the MERLN Institute for Technology-inspired Regenerative Medicine at Maastricht University in the Netherlands invites applications for a post-doctoral position. The post-doctoral researcher will perform cutting-edge research in computational modeling methods applied to regenerative medicine and more specifically, to cell-matrix interactions.

Regenerative medicine (RM) holds the promise to cure many of what are now chronic patients, restoring health rather than protracting decline, bettering the lives of millions and at the same time preventing lifelong, expensive care processes: cure instead of care. The scientific community has made large steps in this direction over the past decade, however our understanding of the fundamentals of cell, tissue and organ regeneration and of how to stimulate and guide this with intelligent biomaterials in the human body is still in its infancy. To date, the RM field has focused on studying cell-biomaterial interactions. Materials properties such as elasticity, topography, hydrophobicity, and porosity have all been shown to influence cell fate, and the introduction of high-throughput combinatorial approaches is expediting research and decoupling the properties to further inform the design of biomaterials. However, in order to improve the design of synthetic biomaterials, it is crucial to understand the physiological cell-ECM interactions and how these influence cell behavior. This research project aims to use in silico models to simulate cell-ECM interactions, improve our fundamental understanding thereof and use the obtained knowledge to design improved synthetic matrices.

More information can be found here:

https://www.academictransfer.com/en/309006/post-doctoral-position-for-the-project-computational-modeling-of-the-cell-matrix-interface-at-the-department-of-cell-biology-inspired-tissue-engineering-cbite-at-the-merln-institute/

For more detailed information you can contact:
dr. A. Carlier, email a.carlier@maastrichtuniversity.nl

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